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Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Etiology/Pathophysiology:
Due to Vitamin C deficiency which leads to defective osseous
connective tissue formation with increased metaphyseal fragility and
massive subperiosteal hemorrhage.
Pathology:
Not applicable
Imaging Findings:
On film see generalized demineralization, loss of normal trabeculae,
and thin cortices. The growth plates are not widened and the
metaphyses are smooth. The white line of Frankel is a dense zone of
provisional calcification with a lucent band beneath this (scorbutic
zone). There is extensive subperiosteal elevation and new bone
reaction along the shafts of bones due to subperiosteal hemorrhage.
The epiphyses are of normal size and shape and are surrounded by a
dense ossification rim (Wimberger's ring).
DDX:
References:
See References Chapter.
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