Additional pediatric resources: SearchingPediatrics.com | PediatricEducation.org | GeneralPediatrics.com | Pediatric Commons
Michael P. D'Alessandro, M.D.
Peer Review Status: Not reviewed
The patient was an 8 year old female with multisystem auto-immune disease and progressive chronic interstitial lung disease. She presented one year ago with fever, weakness, hepatitis and pneumonitis of unknown etiology. She had a repeatedly positive polymerase chain reaction for parvovirus. The lung disease progressed over the last year despite treatment with steroids, cyclosporine, cloxacillin, and gamma globulin. The patient also had 6 courses of Cytoxan for her autoimmune lung disease.
Clinical Physical Exam:
Positive polymerase chain reaction for parvovirus
Clinical Differential Diagnosis:
Bronchiolitis obliterans with organizing pneumonia
Chest film and chest CT exam showed bilateral lower lobe disease.
Images 2 and 3
Imaging Differential Diagnosis:
None was given
An open lung biopsy was performed.
The open lung biopsy showed patchy interstitial pneumonitis with organizing intra-alveolar granulation and fibrin (organizing alveolitis), and necrotizing bronchiolitis with organization and early obliteration.
Bronchiolitis Obliterans with Organizing Pneumonia
Follow-up and Prognosis:
The patient had an uncomplicated post-operative course.
Case 62, Case 63
Next Page | Previous Page | Section Top | Title Page
Please send us comments by filling out our Comment Form.
All contents copyright © 1992-2014 Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. and the authors. All rights reserved.
"Virtual Pediatric Hospital", the Virtual Pediatric Hospital logo, and "A digital library of pediatric information" are all Trademarks of Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D.
Virtual Pediatric Hospital is funded in whole by Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. Advertising is not accepted.
Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.
The information contained in Virtual Pediatric Hospital is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.
This site complies with the HONcode standard for trustworthy health information: