Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
A small cranial vault (microcrania) almost always due to a small brain (micrencephaly). Causes of micrencephaly are genetic / chromosomal defects (phenylketonuria, aminoaciduria, Down's Syndrome), intrauterine infection (TORCH), and intrauterine trauma (radiation).
Have progressive craniofacial disproportion due to lack of brain growth with continued normal growth of the chondrocranium and face. The sutures are narrow and fuse prematurely. The mastoids air cells and paranasal air cells are large. The calvarium is very think and the normal convolutional markings are reduced.
See References Chapter.
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