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Virtual Pediatric Hospital: Paediapaedia: Fibrous Dysplasia of the Skull Paediapaedia: Neurological Diseases

Fibrous Dysplasia of the Skull

Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed


Clinical Presentation:
Varies greatly, depending upon which bones are affected.

Etiology/Pathophysiology:
Extensive proliferation of fibrous tissue which destroys and replaces normal bone. Severe cases are labeled "Leontiasis Ossea"

Pathology:
Not applicable

Imaging Findings:
Predominantly unilateral. See a diffuse, progressive sclerosis and expansion which extends across sutures and synchondroses.

DDX:

References:
See References Chapter.

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