Virtual Pediatric Hospital(tm) : A digital library of pediatric information

Home | Search | About Us | FAQ | Reviews | Contact Us
Follow us on Twitter @pedseducationTwitter icon and @pedsimagingTwitter icon

Additional pediatric resources: SearchingPediatrics.com | PediatricEducation.org Facebook iconTwitter iconRSS icon | GeneralPediatrics.com | Pediatric Commons


Virtual Pediatric Hospital: Paediapaedia: Craniopharyngioma Paediapaedia: Neurological Diseases

Craniopharyngioma

Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed


Clinical Presentation:
May have headaches and increased intracranial pressure, visual disturbances, retarded growth and diabetes insipidus.

Etiology/Pathophysiology:
Arise from neural ectoderm and epithelial elements in Rathke's pouch which is an embryonal outpouching in the floor of the third ventricle. These tumors can be located anywhere in the primitive craniopharyngeal duct that goes from the floor of third ventricle into the body of sphenoid bone and retropharyngeal space. It accounts for 7% of children's brain tumors, and 50% of tumors around the sella. Ninety percent are suprasellar and 10% are intrasellar. Benign and slow growing.

Pathology:
Typically nests or cords of stratified squamous or columnar epithelium present in the tumor. May be cystic, with a high cholesterol content.

Imaging Findings:
Large suprasellar mass with 60-80% having a thin and curvilinear calcification around the edge of the tumor.

On MRI, Can be bright on T1WI and T2WI if it is cystic with a high cholesterol content or if it has methemoglobin within in. Low signal intensity on T1WI and T2WI can be due to cystic lesions high in keratin content or tumors with extensive calcification.

DDX:
Suprasellar masses

References:
See References Chapter.

Section Top | Title Page


Follow us on Twitter @pedseducationTwitter icon and @pedsimagingTwitter icon

Additional pediatric resources: SearchingPediatrics.com | PediatricEducation.org Facebook iconTwitter iconRSS icon | GeneralPediatrics.com | Pediatric Commons


Home | Search | About Us | FAQ | Reviews | Contact Us

Virtual Pediatric Hospital is curated by Donna M. D'Alessandro, M.D. [Google+ Profile] and by Michael P. D'Alessandro, M.D.

Please send us comments by filling out our Comment Form.

All contents copyright 1992-2014 Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. and the authors. All rights reserved.

"Virtual Pediatric Hospital", the Virtual Pediatric Hospital logo, and "A digital library of pediatric information" are all Trademarks of Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D.

Virtual Pediatric Hospital is funded in whole by Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. Advertising is not accepted.

Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.

The information contained in Virtual Pediatric Hospital is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.

URL: http://www.virtualpediatrichospital.org/

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.