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Virtual Pediatric Hospital: Paediapaedia: Abscess, Brain Paediapaedia: Neurological Diseases

Abscess, Brain

Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed


Clinical Presentation:
Headache, vomiting, personality change, focal neurologic deficits, seizures.

Etiology/Pathophysiology:
Due to seeding from inflammatory disease in the temporal bone or paranasal sinuses, subacute bacterial endocarditis, cystic fibrosis, or congenital heart disease with a right to left shunt allowing venous blood unfiltered by the capillaries to reach the brain.

Pathology:
Not applicable

Imaging Findings:
The lesion consists of a necrotic, supprative center encapsulated by a peripheral rim of hyperemic granulation tissue. It is normally located at the gray matter / white matter junction, and is surrounded by edema. The granulation tissue shows ring enhancement with contrast.

DDX:

References:
See References Chapter.

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