Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed
Have erythroblastemia and marked changes in the size and shape of the red blood cell. The treatment is splenectomy.
Radiographic findings reflect the increased hematopoiesis. A generalized osteopenia is seen with decreased trabecular prominence, a widened medullary space, and thin cortices. These findings are most marked in the hands and femurs. "Hair on end" appearance is seen in the skull. Twenty-three percent of patients greater than 10 years old have premature epiphyseal fusion. Extramedullary hematopoiesis can present as lobulated masses in the mediastinum contiguous to the spine. Hemosiderin is deposited in various organs, particularly the liver. Cardiomegaly is often seen secondary to high output congestive heart failure.
See References Chapter.
Section Top | Title Page
Please send us comments by filling out our Comment Form.
All contents copyright © 1992-2018 Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. and the authors. All rights reserved.
"Virtual Pediatric Hospital", the Virtual Pediatric Hospital logo, and "A digital library of pediatric information" are all Trademarks of Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D.
Virtual Pediatric Hospital is funded in whole by Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. Advertising is not accepted.
Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.
The information contained in Virtual Pediatric Hospital is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.