Virtual Pediatric Hospital(tm) : A digital library of pediatric information

Home | About | FAQ | Reviews | Search

Virtual Pediatric Hospital: Paediapaedia: Meconium Plug (Small Left Colon Syndrome) Paediapaedia: Gastrointestinal Diseases

Meconium Plug (Small Left Colon Syndrome)

Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed

Clinical Presentation:
Generalized abdominal distension, failure to pass meconium, and delayed onset of vomiting. Seen classically in infants of diabetic mothers or mothers who have received magnesium sulfate for preeclampsia during pregnancy.

Ganglion cells are present but immature and this causes a functional colonic inertia which leads to a meconium plug forming in the colon, that causes obstruction and a narrowed descending colon. A certain percentage of these patients also have Hirschsprung disease, so they must be followed closely to see if they develop symptoms of chronic constipation and require a rectal biopsy to rule out Hirschsprung Disease.

Present, but functionally immature ganglion cells.

Imaging Findings:
An enema shows a normal sized rectum and small caliber sigmoid and descending colon with a transition zone in colonic caliber occurring at the level of the splenic flexure. The meconium plugs are often outlined by the enema contrast material.The enema is most often curative.

Low Bowel Obstruction

See References Chapter.

Section Top | Title Page

Additional pediatric resources: | Facebook iconTwitter iconRSS icon |

Follow us on Twitter @pedseducationTwitter icon and @pedsimagingTwitter icon

About Us | FAQ | Reviews | Contact Us | Search

Virtual Pediatric Hospital is curated by Donna M. D'Alessandro, M.D. and by Michael P. D'Alessandro, M.D.

Please send us comments by filling out our Comment Form.

All contents copyright © 1992-2016 Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. and the authors. All rights reserved.

"Virtual Pediatric Hospital", the Virtual Pediatric Hospital logo, and "A digital library of pediatric information" are all Trademarks of Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D.

Virtual Pediatric Hospital is funded in whole by Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. Advertising is not accepted.

Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.

The information contained in Virtual Pediatric Hospital is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.