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Virtual Pediatric Hospital: Paediapaedia: Kartagener Syndrome (Immotile Cilia Syndrome) Paediapaedia: Chest and Airway Diseases

Hodgkin's Lymphoma

Michael P. D'Alessandro, M.D.
Peer Review Status: Internally Peer Reviewed


Clinical Presentation:
Systemic symptoms include fever, malaise, anorexia, and weight loss. Respiratory symptoms can result from compression of the trachea and lung by the mediastinal mass. Lymphoma - including Hodgkin's and Non-Hodgkin's - accounts for 10% of all malignant disease in children. Thirty-three percent of children presenting with lymphoma present with an anterior or middle mediastinal mass.

Etiology/Pathophysiology:
Not applicable

Pathology:
Not applicable

Imaging Findings:
Classically, a bulky, multinodular mediastinal mass originating in the anterior mediastinum is seen. Mediastinal, paratracheal and hilar lymphadenopathy is often seen. Pleural effusion is present in 15% due to spread of tumor between the pleura and anterior chest wall.

DDX:

References:

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