Additional pediatric resources: GeneralPediatrics.com | PediatricEducation.org | SearchingPediatrics.com
Correlapaedia - a Correlative Encyclopedia of Pediatric Imaging, Surgery, and Pathology
The patient was an 8 year old female with a 5 day history of flu like symptoms and a 3 day history of abdominal distension. She was seen in her pediatrician's office where she was found to be orthostatic and her abdominal distension was noted and she was referred to the hospital.
Clinical Physical Exam:
Febrile to 38.9 C. Abdomen was distended with superficial collateral veins and a large mass was palpable. A fluid wave was present, along with tympany.
Images 1 and 2
A paracentesis done upon admission to the hospital was negative for tumor cells. Serum tumor markers obtained prior to surgery revealed an AFP of 12,254 and a beta HCG of 3.6.
Clinical Differential Diagnosis:
Ovarian mass, rhabdomyosarcoma
An abdominal film from the day of admission showed a pelvic mass. An abdominal ultrasound exam from the day of admission showed a large heterogeneous mass in the lower abdomen with no clear organ of origin. An MRI exam from the third hospital day pointed to the right ovary as the organ of origin of the mass. A chest CT obtained post operatively (not provided) showed no evidence of metastatic disease in the chest, and a bone scan obtained post operatively (not provided) showed no evidence of bone metastases.
Images 4 and 5
Images 6 and 7
Imaging Differential Diagnosis:
On the fourth hospital day the patient underwent an exploratory laparotomy through a midline incision. The tumor was seen to arise from the right ovary, and a portion of the omentum was adherent to the tumor. The left ovary had two firm nodules within it that were wedge biopsied. The tumor was delivered from the peritoneal cavity without spillage of tumor. The patient had a right salpingo-oophorectomy with partial omentectomy, left ovary biopsy, peritoneal biopsy, and nodal biopsies. Frozen sections of the tumor were positive for malignancy. A small peritoneal implant was noted at the dome of the bladder and was excised, with frozen section examination suggesting the presence of malignant cells.
Examination of the surgical specimen revealed findings characteristic of endodermal sinus tumor.
Images 9 and 10
Ovarian Endodermal Sinus Tumor with peritoneal metastases.
Follow-up and Prognosis:
The patient had an uncomplicated post-operative course. She received chemotherapy.
Case 40, Case 42
Please send us comments by filling out our Comment Form.
All contents copyright © 1992-2018 Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. and the authors. All rights reserved.
"Virtual Pediatric Hospital", the Virtual Pediatric Hospital logo, and "A digital library of pediatric information" are all Trademarks of Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D.
Virtual Pediatric Hospital is funded in whole by Donna M. D'Alessandro, M.D. and Michael P. D'Alessandro, M.D. Advertising is not accepted.
Your personal information remains confidential and is not sold, leased, or given to any third party be they reliable or not.
The information contained in Virtual Pediatric Hospital is not a substitute for the medical care and advice of your physician. There may be variations in treatment that your physician may recommend based on individual facts and circumstances.